Mounjaro
Mounjaro is a once-weekly injection for weight loss and weight maintenance in adults.
It contains an active substance called tirzepatide. Mounjaro activates the actions of 2 natural substances in your body, called glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1).
Mounjaro primarily works by regulating your appetite, giving you a sense of satiety (‘fullness’), making you feel less hungry and experience less food cravings. This will help you eat less food and reduce your body weight. It is important to continue to follow the advice on diet and exercise given to you by your healthcare professional.
We use same UK pharmaceutical wholesalers that also supply medicines to the NHS. This guarantees your injections follow a secure and safe supply chain.
Am I eligible for weight loss injections ?
We may prescribe Mounjaro together with a reduced-calorie diet and increased physical activity for weight loss and to help keep your weight under control if you are between ages 18 to 75 and who has:
A body mass index (BMI) of 30 kg/m² or greater (obesity) or
A BMI of at least 27 kg/m² but less than 30 kg/m² (overweight) and weight-related health problems such as:
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Pre-diabetes
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High blood pressure
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Abnormal levels of fats in the blood
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Obstructive sleep apnoea
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History of heart attack, stroke or blood vessel problems
We are unable to offer weight loss injections for diabetic patients as your overall management is best maintained by your diabetic team.
You should not take Mounjaro if:
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You have severe problems with food digestion or food remaining in your stomach for longer than normal (including severe gastroparesis)
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You have ever had pancreatitis (inflammation of the pancreas which may cause severe pain in the stomach and back, which does not go away)
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You have a problem with your eyes (diabetic retinopathy or macular oedema)
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You are using a sulphonylurea (diabetes medicine) or insulin, as low blood sugar (hypoglycaemia) can occur. Your healthcare professional may need to change your dose of these other medicines to reduce this risk
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You have hepatic (liver) or renal (kidney) impairment
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You have been diagnosed with an eating disorder
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How Mounjaro works
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Reducing how much food you crave and eat
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Slowing down how quickly food leaves your stomach. This lessens over time
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Regulating fat utilisation
How effective is Mounjaro
​Studies have shown that 96% of patients will lose weight with Mounjaro.
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By 72 weeks patients with Mounjaro can
achieve an average weight loss of:
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22.5% on the 15mg dose
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21.4% on the 10mg dose
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16.0% on the 5mg dose
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This is with dose increments as clinically needed throughout that period and along with lifestyle changes. (The SURMOUNT-1 clinical trial)
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*In the Semaglutide (Ozempic/Wegovy) clinical trials patients lost up to 15% of their body weight after 68 weeks on the maintenance dose.
**In the Liraglutide (Saxenda) clinical trials patients on average lost 6.3% of their body weight after 56 weeks on the maintenance dose.
Get your full guide
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Introducing the Mounjaro KwikPen
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How much to use
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Choosing when to use Mounjaro
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Preparing to inject with Mounjaro KwikPen
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Choosing your injection site
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Injecting with your Mounjaro KwikPen
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After your Mounjaro KwikPen injection
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Storage & disposal
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Managing missed doses
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Possible side effects
How to manage potential side effects of Mounjaro
Like all medicines, Mounjaro can cause side effects, although not everyone gets them. The most common side effects include:
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Feeling sick (nausea). Most common when first starting Mounjaro but then improves for most patients
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Diarrhoea
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Being sick (vomiting)
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Constipation
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These side effects are most common when first starting Mounjaro and usually improve over time. Our clinicians will guide you.
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If you experience nausea then these tips can help:
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Eat smaller meals. E.g split your 3 main meals into 4 or more smaller meals in a day
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Stop eating when you feel full
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Avoid food with high fat content
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Eating bland foods like toast, crackers, or rice
